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In recent trials, digoxin has been shown to reduce morbidity associated with congestive heart failure but to have no demonstrable effect on survival.
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therefore, patients may need to be monitored when digoxin is taken concomitantly with prilosec.
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digoxin is relatively contraindicated in patients with carotid sinus hypersensitivity because the drug increases vagal tone.
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1 maurizio sessa , annamaria mascolo , mikkel porsborg andersen , giuseppe rosano , francesco rossi , annalisa capuano , christian torp-pedersen , thomas berger , effect of chronic kidney diseases on mortality among digoxin users treated for non-valvular atrial fibrillation a nationwide register-based retrospective cohort study, plos one , 2016 , 11 , 7, e0160337 crossref 2 hsiang-wen lin , hsin-hui tsai , i-wen yu , arun kumar , man-pin wu , would it matter to expose elderly patients who took digoxin to chinese medications.
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drug interactions no significant drug-drug pharmacokinetic interactions have been found in interaction studies with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital.
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hypokalemia and hypomagesemia sensitize the myocardium to digoxin digoxin toxicity can be precipitated by conditions such as hypokalemia, hypomagnesemia or hypothyroidism, even if the digoxin level is normal.
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